Table 2.
Comparison of clinical characteristics between eyes with and without DME.
| Characteristic | DME present (n = 36) | DME absent (n = 72) | p-value |
|---|---|---|---|
| Age, y | 60.50 (56.00–64.00) | 56.00 (55.00–58.00) | - |
| Female, n (%) | 17 (47.22%) | 34 (47.22) | - |
| Right eye, n (%) | 18 (50%) | 18 (50%) | - |
| CMT, μm | 428.00 (397.00–502.00) | 255.00 (248.51–262.00) | <0.001 * |
| CMV (within 1 mm), mm3 | 0.34 (0.31–0.39) | 0.20 (0.19–0.21) | <0.001 * |
| CMV (within 3 mm), mm3 | 3.19 (2.90–3.48) | 2.22 (2.19–2.28) | <0.001 * |
| CMV (within 5 mm), mm3 | 8.66 (7.77–8.99) | 6.11 (5.97–6.25) | <0.001 * |
| MA count (panretina), n | 318.00 (262.00–356.50) | 252.00 (169.00–284.00) | 0.044 * |
| MA count (PoA), n | 213.50 (177.00–237.00) | 152.50 (114.00–191.00) | 0.012 * |
| MA count (MPA), n | 72.50 (61.00–105.89) | 57.50 (39.00–89.00) | 0.149* |
| MA count (FPA), n | 12.00 (7.00–20.00) | 10.50 (7.00–17.00) | 0.977* |
| ISI (panretina), % | 2.79 (1.59–4.48) | 1.90 (0.99–3.53) | 0.118* |
| ISI (PoA), % | 5.10 (2.36–10.05) | 2.65 (1.32–4.41) | 0.022 * |
| ISI (MPA), % | 1.69 (0.49–2.91) | 1.22 (0.50–2.71) | 0.590* |
| ISI (FPA), % | 0.00 (0.00–0.24) | 0.00 (0.00–0.17) | 0.595* |
| Leakage index (panretina), % | 8.90 (7.90–11.85) | 4.53 (3.05–5.76) | <0.001 * |
| Leakage index (PoA), % | 21.22 (20.20–24.78) | 9.87 (7.11–11.96) | <0.001 * |
| Leakage index (MPA), % | 3.66 (2.43–5.05) | 1.65 (0.96–2.31) | 0.004 * |
| Leakage index (FPA), % | 1.42 (0.51–2.97) | 0.64 (0.25–1.04) | 0.077* |
DME, diabetic macular edema; CMT, central macular thickness; CMV, central macular volume; MA count, microaneurysm count; ISI, ischemic index; PoA, posterior area; MPA, mid-periphery area; FPA, far-periphery area.
All quantitative parameters are expressed as median (95% CI).
*
p-value determined by Mann–Whitney U-test. Bold font indicates statistical significance.