Table 3.
Comparison of clinical characteristics between eyes with and without PDR.
| Characteristic | PDR present (n = 43) | PDR absent (n = 65) | p value |
|---|---|---|---|
| Age, y | 55.00 (51.00–57.00) | 58.00 (56.00–61.50) | - |
| Female, n (%) | 19 (44.19%) | 32 (49.23%) | - |
| Right eye, n (%) | 20 (46.51) | 34 (52.31) | - |
| CMT, μm | 282.00 (262.00–310.00) | 266.00 (259.00–283.00) | 0.361 |
| CMV (within 1 mm), mm3 | 0.22 (0.21–0.24) | 0.21 (0.21–0.22) | 0.350 |
| CMV (within 3 mm), mm3 | 2.50 (2.22–2.67) | 2.32 (2.27–2.39) | 0.770 |
| CMV (within 5 mm), mm3 | 7.07 (6.16–7.25) | 6.38 (6.14–6.49) | 0.516 |
| MA count (panretina), n | 284.00 (250.00–339.00) | 260.00 (175.00–317.87) | 0.222 |
| MA count (PoA), n | 195.00 (141.54–215.00) | 168.00 (114.00–207.00) | 0.609 |
| MA count (MPA), n | 91.00 (62.00–105.00) | 55.00 (35.00–69.00) | 0.041 |
| MA count (FPA), n | 17.00 (8.00–22.00) | 8.00 (5.50–14.00) | 0.087 |
| ISI (panretina), % | 4.21 (2.52–6.62) | 1.06 (0.44–1.87) | <0.001 |
| ISI (PoA), % | 7.72 (5.48–10.29) | 1.68 (0.94–2.69) | <0.001 |
| ISI (MPA), % | 3.35 (1.94–6.01) | 0.48 (0.18–1.04) | <0.001 |
| ISI (FPA), % | 0.23 (0.00–1.26) | 0.00 (0.00–0.00) | 0.006 |
| Leakage index (panretina), % | 8.65 (6.71–11.28) | 3.76 (3.06–5.62) | <0.001 |
| Leakage index (PoA), % | 20.41 (12.51–23.30) | 9.38 (7.10–13.47) | <0.001 |
| Leakage index (MPA), % | 4.19 (2.63–6.6.09) | 1.12 (0.66–2.17) | <0.001 |
| Leakage index (FPA), % | 1.23 (0.63–2.62) | 0.45 (0.04–1.04) | 0.014 |
PDR, proliferative diabetic retinopathy; CMT, central macular thickness; CMV, central macular volume; MA count, microaneurysm count; ISI, ischemic index; PoA, posterior area; MPA, mid-periphery area; FPA, far-periphery area.
All quantitative parameters are expressed as median (95% CI). *p-value determined by Mann–Whitney U-test. Bold font indicates statistical significance.