Table 4.

Optimal cut-off values and coordinates of the ROC curve for determining the presence of DME.

Characteristic	Cut-off values	Sensitivity%	Specificity%	Youden index
MA count (panretina), n	>153	88.89	37.50	0.2639
MA count (PoA), n	>129	83.33	45.83	0.2917
ISI (panretina), %	>0.34	100.00	27.78	0.2778
ISI (PoA), %	>1.01	94.44	36.11	0.3056
Leakage index (panretina), %	>6.709	72.22	69.44	0.4167
Leakage index (PoA), %	>16.704	75.00	75.00	0.5000

MA count, microaneurysm count; ISI, ischemic index; PoA, posterior area.