Table 1.
Summary of patient demographics, clinical factors, and treatment variables (n = 12)
| Value | |
|---|---|
| Age (yr) | 65.5 (56–83) |
| <65 | 5 (42) |
| ≥65 | 7 (58) |
| Sex | |
| Male | 7 (58) |
| Female | 5 (42) |
| Race | |
| White | 5 (42) |
| Hispanic | 2 (17) |
| Asian | 5 (42) |
| Diagnosis | |
| HCC | 9 (75) |
| Cholangiocarcinoma | 2 (17) |
| Neuroendocrine liver metastasis | 1 (8) |
| ECOG performance status | |
| 0 | 7 (58) |
| 1 | 4 (33) |
| 2 | 1 (8) |
| Child–Pugh classification | |
| A | 9 (75) |
| B | 3 (25) |
| C | 0 (0) |
| Location of PVTT | |
| Segmental branch | 2 (17) |
| Left/right PV | 9 (75) |
| Main PV | 1 (8) |
| 90Y dose (Gy) | 104.3 (83.3–131.7) |
| 90Y volume (mL) | 846 (675–1,068) |
| Five-fraction SBRT dose (Gy) | 32.5 (27.5–50) |
| <30 | 3 (25) |
| 30–35 | 4 (33) |
| 40–45 | 3 (25) |
| ≥50 | 2 (17) |
| Days between 90Y and SBRT | |
| <30 | 1 (8) |
| 30–60 | 5 (42) |
| 60–90 | 2 (17) |
| >90 | 4 (33) |
| PTV volume (mL) | 91.3 (14.7–623.2) |
| <50 | 2 (17) |
| 50–100 | 5 (42) |
| 100–250 | 2 (17) |
| 250–500 | 2 (17) |
| >500 | 1 (8) |
| Previous treatments | |
| Surgical resection | 0 (0) |
| Liver transplant | 0 (0) |
| Systemic therapy | 0 (0) |
| Maintenance therapy afterwards | |
| Yes | 7 (58) |
| No | 5 (42) |
Values are presented as median (range) or number (%).
HCC, hepatocellular carcinoma; ECOG, Eastern Cooperative Oncology Group; PVTT, portal vein tumor thrombosis; PV, portal vein; 90Y, yttrium-90; SBRT, stereotactic body radiation therapy; PTV, planning target volume.