Table 1.

Patients' background and clinical data.

N	85
Age (years)	62.3 ± 9.5 (37-79)
Sex (M/F)	51.8/48.2%
Education	Elementary School	25.9%
	Junior high School	41.2%
	High school	25.9%
	University	7.1%
Occupation	Retired	58.8%
	Unoccupied	2.4%
	Occupied	38.8%
Age at onset (years)	59.7 ± 9.6 (35-77)
Age at diagnosis (years)	60.7 ± 9.6 (35-77)
Diagnostic delay (years)	0.99 ± 0.63 (0-4)
Disease duration (years)	1.6 ± 1.73 (0-13)
Site of onset	Bulbar	20%
	Spinal	80%
Phenotype*	Classical	76.2%
	Bulbar	16.7%
	Pyramidal	3.6%
	FAS	2.4%
	FLS	1.2%
MMSE	27.61 ± 2.1 (23-30)
ADI-12	25.56 ± 5.61 (13-43)
HADS-A	6.59 ± 3.67 (1-17)
HADS-D	5.14 ± 3.14 (0-14)
MQoL	Total	6.8 ± 1.25 (3.54-9.5)
	Physical	5.81 ± 2.27 (1.25-10)
	Psychological	5.03 ± 1.95 (0.83-9.5)
	Existential	7.21 ± 1.64 (0-10)
	Support	8.11 ± 1.59 (0-10)

FAS, flail arm syndrome; FLS, flail leg syndrome; MMSE, Mini-Mental State Examination; ADI-12, ALS Depression Inventory-12; HADS-A/-D, Hospital Anxiety and Depression Scale-Anxiety/-Depression; MQoL, McGill Quality of Life Questionnaire.

^*Piemonte and Valle d'Aosta Register for ALS (PARALS) (10).