Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Sep 24;9:666303. doi: 10.3389/fcell.2021.666303

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Tan, Zhang, Li, Zhan, Qiao, Wu, Sun, Huang, Zhang, Zhang, Li, Li and Pan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Molecular defects in the oviduct of Lgr4-deficient mice. (A) RNA-seq for mouse oviducts (the estrus stage). Clustered heat map of log2-transformed FPKMs showing the differentially expressed genes after LGR4 deletion. Indicated genes are marked on the right side of the heat map. (B) Gene Ontology analysis. (C) RT-PCR assay showing the relative changes of some representative small molecular factor genes. (D) IHC assays to detect the protein level of OVGP1 in the WT or Lgr4-deficient oviducts. (E) IHC assays to detect the location of PAX8 in the WT and Lgr4-deficient oviductal epithelial cells. ^∗p ≤ 0.05; ^∗∗p ≤ 0.01. Scale bar, 25 μm in (D,E). RT-PCR, reverse transcription polymerase chain reaction; IHC, immunohistochemistry.