Table 3.
Changes in anthropometric and laboratory variables of quadruple regimen-maintained participants during study period (n=270)
| Variable | No. | Baseline | 12 months | P value |
|---|---|---|---|---|
| Weight, kg | 155 | 70.7±12.4 | 70.6±12.0 | 0.641 |
| BMI, kg/m2 | 151 | 25.8±3.1 | 25.7±3.1 | 0.636 |
| SBP, mm Hg | 198 | 126.4±14.1 | 125.0±12.7 | 0.162 |
| DBP, mm Hg | 198 | 73.8±9.3 | 72.8±10.0 | 0.177 |
| HbA1c, % | 270 | 8.9±1.2 | 7.8±1.3 | ≤0.001 |
| Total cholesterol, mg/dL | 135 | 157.3±42.5 | 150.6±38.0 | 0.054 |
| LDL-C, mg/dL | 123 | 92.3±36.0 | 84.5±30.3 | 0.008 |
| HDL-C, mg/dL | 121 | 45.6±11.1 | 47.3±10.6 | 0.080 |
| Triglyceride, mg/dL | 130 | 162.8±99.4 | 132.7±78.2 | ≤0.001 |
| Serum creatinine, mg/dL | 164 | 0.9±0.2 | 0.9±0.3 | 0.607 |
| eGFR, mL/min/1.73 m2 | 104 | 88.6±21.4 | 89.4±24.7 | 0.647 |
| AST, units/L | 153 | 24.4±13.7 | 22.0±9.3 | 0.005 |
| ALT, units/L | 153 | 27.5±15.4 | 23.4±11.9 | 0.001 |
| GGT, units/L | 47 | 49.3±52.1 | 37.8±41.1 | 0.011 |
Values are presented as mean±standard deviation.
BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; HbA1c, glycosylated hemoglobin; LDL-C, low density lipoprotein cholesterol; HDL-C, high density lipoprotein cholesterol; eGFR, estimated glomerular filtration rate; AST, aspartate aminotransferase; ALT, alanine aminotransferase; GGT, gamma-glutamyl transferase.