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. 2021 Oct 8;227:113910. doi: 10.1016/j.ejmech.2021.113910

Table 5.

The comparison between LNP and liposome.

LNP Liposome
Similarities Particle size distribution, shape, lipid composition, positive charge
Differences 1 Phospholipid monolayer structure 1 Phospholipid bilayer structure
2 The microfluidic preparation method 2 The thin film dispersion method
3 Self assembly 3 High energy dispersion