Table 4.
The application of metabolomics for exploring the candidate biomarkers for ovarian cancer.
| Applied Methods | Subjects | Metabolite Symbol(s) | Ref. |
|---|---|---|---|
| UPLC/Q-TOF MS | Serum | 2-piperidinone, 1-heptadecanoylglycerophosphoethanolamine | (153) |
| Wide spectrum targeted metabolomics | Serum | lysoPC a C16:1, PC aa C32:2, PC aa C34:4, PC aa C 36:6 | (154) |
| GC-MS | Serum | EFA (C16:0), EFA (C18:0), FFA(C16:0) | (155) |
| HILIC, MS/MS | Serum | combination of serum maltose, maltotriose, raffinose, and mannitol | (156) |
| UPLC-MS | Serum | CPG | (157) |
| UPLC-MS | Plasm | piperine, 3-indolepropionic acid, 5-hydroxyindoleacetaldehyde hydroxyphenyllactate | (158) |
| UPLC/Q-TOF/MS | Plasm | adrenoyl ethanolamide, LysoPCs, LysoPE | (159) |
| RRLC-MS | Plasm | hydroxyphenyllactic acid, coproporphyrinogen, uric acid, lysine, 3-(3,5-diiodo-4-hydroxyphenyl) lactate, 24,25-hydroxyvitamin D3, carnitine, creatinine, l-beta-aspartyl-l-glutamic acid phosphohydroxypyruvic acid | (160) |
| UPLC-QTOF/MS | Urine | N4-acetylcytidine, succinic acid, urate-3-ribonucleoside, pseudouridine | (161) |
| HILIC, RPLC, MS | Urine | homovanillic acid sulfate, phytosphingosine, hippuric acid, pseudouridine | (162) |
| GC/TOF-MS | Tissues | glucose | (163) |