TABLE 1.
GlyR variant | Whole cell GlyR β (%) | p-values | n | GlyR variant + eGFP gephyrin | whole cell geph (%) | p-values | Surface fraction geph (%) | p-values | n |
GlyR α1β | 100 ± 17 | 3 | GlyR α1β | 100 ± 28 | 100 ± 23 | 4 | |||
GlyR α1βY252S | 58 ± 2 | p = 0.07 | 3 | GlyR α1βY252S | 136 ± 37 | p = 0.5 | 191 ± 53 | p = 0.2 | 4 |
GlyR α1βS321F | 72 ± 7 | p = 0.2 | 3 | GlyR α1βS321F | 191 ± 51 | p = 0.2 | 190 ± 42 | p = 0.1 | 4 |
GlyR α1βA455P | 98 ± 18 | p = 0.9 | 3 | GlyR α1βA455P | 209 ± 39 | p = 0.6 | 168 ± 13 | *p = 0.043 | 4 |
Significance values: *p < 0.05, n = number of experiments.