Table 1.
Baseline variables of subtypes and their stability at 3 years.
| Variable | All | TD | Indeterminate | PIGD | Statistics* | p + |
|---|---|---|---|---|---|---|
| (n = 170) | (n = 103) | (n = 21) | (n = 46) | |||
| Age (years) | 69.3 ± 9.7 | 68.8 ± 8.10 | 73.5 ± 9.42 | 68.4 ± 12.3 | 2.35 | 0.099 |
| Gender (male, %) | 100 (58.8) | 61 (59.2) | 15 (71.4) | 24 (52.2) | 2.22 | 0.329 |
| Education (years) | 9.55 ± 4.61 | 9.80 ± 4.26 | 9.14 ± 5.47 | 9.19 ± 4.98 | 0.386 | 0.693 |
| LEDD, mg | 233.56 ± 177.72 | 192.75 ± 144.21 | 257.76 ± 177.72 | 276.92 ± 232.91 | 6.09 | 0.048 |
| Disease duration (months) | 6.35 ± 6.50 | 6.01 ± 5.89 | 5.52 ± 5.51 | 7.49 ± 8.03 | 1.02 | 0.361 |
| MMSE | 26.66 ± 3.34 | 26.88 ± 3.12 | 26.67 ± 2.65 | 26.15 ± 4.03 | 0.760 | 0.469 |
| MDS-UPDRS Part III | 23.51 ± 11.36 | 22.66 ± 11.24 | 23.09 ± 12.69 | 25.61 ± 10.98 | 1.08 | 0.342 |
| Stability, N (% of subtypes) | ||||||
| Stable | 64 (62.1) | 1 (4.8) | 23 (50.0) | 23.1 | <0.001 | |
| Unstable | 39 (37.9) | 20 (95.2) | 23 (50.0) |
Mean ± standard deviation and median (interquartile) reported for continuous variables; frequency (%) reported for categorical variables.
ANOVA or Kruskal–Wallis test (depending on the normality assumption) for continuous variables and chi-square for categorical variables; ANOVA was performed for age, gender, disease duration, MDS-UPDRS III, and MMSE; Kruskal–Wallis was conducted for LEDD; and chi-square for gender and stability.
Reported statistics is chi-square for categorical variables and non-normal continuous variables; F value for normal continuous variables; degree of freedom = 2 for all variables as the grouping variable include three categories.
LEDD, baseline levodopa equivalent dosages; TD, tremor-dominant subtype; PIGD, postural instability gait subtype; MMSE, Mini-Mental State Examination.
Significant values are indicated in bold.