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. 2021 Sep 24;12:704906. doi: 10.3389/fneur.2021.704906

Table 2.

Multivariable analysis of baseline variables in predicting subtype stability.

Baseline variables Univariate Multivariable*
OR (95% CI) P Chi-square** OR (95% CI) P Chi-square**
Tremor subtype 36.7
Age, years 1.03 (−1.13, 1.24) 0.178 1.85 1.04 (0.98, 1.11) 0.154
Gender (female) 0.41 (0.18, 0.91) 0.037 4.42 0.35 (0.12, 0.98) 0.047
Education, years 0.98 (0.88, 1.06) 0.176 6.75 0.92 (0.81, 1.05) 0.237
LEDD, mg 0.99 (0.99, 1.00) 0.037 4.52 0.99 (0.98, 0.99) 0.006
TD/PIGD ratio 1.72 (1.30, 2.26) <0.001 23.7 1.77 (1.29, 2.43) <0.001
Disease duration, years 0.99 (0.92, 1.05) 0.780 0.077 0.98 (0.90, 1.07) 0.766
MMSE 0.96 (0.84, 1.10) 0.623 0.247 1.01 (0.85, 1.19) 0.892
PIGD subtype 5.06
Age 1.01 (0.96, 1.06) 0.694 0.159 0.99 (0.93, 1.06) 0.884
Gender 1.41 (0.44, 4.53) 0.555 0.349 1.92 (0.50, 7.27) 0.337
Education 1.01 (0.89, 1.13) 0.881 0.022 1.09 (0.93, 1.28) 0.275
LEDD 1.00 (0.99, 1.00) 0.415 0.704 1.00 (0.99, 1.00) 0.780
TD/PIGD ratio 0.21 (0.01, 2.83) 0.242 1.40 0.16 (0.01, 2.77) 0.211
Disease duration 0.99 (0.92, 1.05) 0.780 0.077 0.96 (0.88, 1.06) 0.493
MMSE 0.91 (0.782, 1.07) 0.300 1.18 0.85 (0.66, 1.09) 0.223
*

Multivariable logistical regression model. Multivariable model is only provided for tremor-dominant subtype and PIGD subtype.

**

Chi-square statistics with one degree of freedom is reported for each variable.

LEDD, levodopa equivalent daily dose; MMSE, Mini-Mental State Examination; TD, tremor-dominant subtype; PIGD, postural instability gait subtype; OR, odds ratio; CI, confidence interval.

Significant values are indicated in bold.