Table 3.
CD4 immunogenicity and antigenicity of selected peptides.
| Peptide id | Peptide Sequence | Peptide core | Immunogenicity Score | Combined Score |
|---|---|---|---|---|
| CD4 Immunogenicity | ||||
| A26 | SWMESDFRVYSSANN | FRVYSSANN | 91.1108 | 49.64432 |
| A26 | DFRVYSSANNCTFEY | FRVYSSANN | 82.9956 | 46.39824 |
| A194 | MFVFLVLLPLVSSQCVNLTTRTR | FNVGVYFAS | 91.22 | 48.125 |
| A349 | RFDNPVLPFNVGVYFASTEK | LLPLVSSQC | 83.4206 | 47.64304 |
| A343 | NLMEFVFKNIDGYFK | FKNIDGYFK | 77.9889 | 42.59556 |
| Antigenicity | ||||
| Peptide id | Peptide Sequence | Antigenic motifs | Length | Antigenic propensity |
| A26 | SWMESDFRVYSSANNCTFEYVSQPFLMDLERKPGNFNNLR | DFRVYSS, TFEYVSQPFLM | 40 | 0.9981 |
| A194 | MFVFLVLLPLVSSQCVNLTTRTR | FLVLLPLVSSQCVNL | 23 | 1.1110 |
| A349 | RFDNPVLPFNVGVYFASTEK | NPVLPFNVGVYFA | 20 | 1.0446 |
| A343 | QGNFKNLMEFVFKNIDGYFK | LMEFVFK | 20 | 0.9867 |
| B-cell linear epitopes | ||||
| Peptide id | Peptide Sequence | Epitope core | Length | |
| A26 | SWMESDFRVYSSANNCTFEYVSQPFLMDLERKPGNFNNLR | FRVYSSANN, DLERKPGNFN | 40 | |
| A194 | MFVFLVLLPLVSSQCVNLTTRTR | RF | 23 | |
| A349 | RFDNPVLPFNVGVYFASTEK | LVSSQCVNLT | 20 | |
| A343 | QGNFKNLMEFVFKNIDGYFK | QG | 20 | |