Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Sep 24;12:727000. doi: 10.3389/fphys.2021.727000

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Sun, Pan, Karey, Chen, Pinkerton, Wilson and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Effects of SHS on AP upstroke characteristics of the first 15 APs during step current injections. (A) Absolute AP peak voltage. There was no significant exposure effect on the AP peak whether grouping the data with same injected currents (A1), total number of spikes (A2) or membrane voltages (A3). (B) AP amplitude (measured from voltage threshold to AP peak). SHS exposure group had significantly lower AP amplitude when grouped with same injected currents (B1) or total number of spikes (B2) but not with same membrane voltages (B3). (C) AP maximum rise rate. Compared to the FA group, the SHS group had a lower rise rate at the same injected current (C1). There was no difference when grouping data by total number of spikes (C2) or membrane voltages (C3). (D) Three-way repeated measures ANOVA results. CVTS, injected current, membrane voltage, or total spikes. *p < 0.05 SHS vs. FA, ^†p < 0.05 main effect for membrane voltage.