Table 2.
Descriptive Statistics for the analyzed PTSD cases, depression cases, and controls.
| Region | Control | PTSD | p (PTSD vs Control) | MDD | p (MDD vs Control) | |
|---|---|---|---|---|---|---|
| dlPFC |
N | 24 | 38 | 32 | ||
| Sex = M (%) | 16 (66.67) | 18 (47.37) | 0.22 | 21 (65.63) | 1.00 | |
| AgeDeath mean (SD) | 46.53 (9.97) | 40.98 (11.64) | 0.059 | 41.24 (10.90) | 0.068 | |
| PMI mean (SD) | 29.56 (7.02) | 28.37 (8.24) | 0.56 | 27.31 (7.50) | 0.26 | |
| White non-Hispanic ancestrya n, (%) | 15 (62.50) | 31 (81.60) | 0.17 | 27 (84.40) | 0.12 | |
| Smoking (%) | 7 (29.17) | 28 (73.68) | 0.0015 | 22 (68.75) | 0.0077 | |
| Military Service (%) | 1 (4.17) | 15 (39.47) | 0.0052 | 4 (12.50) | 0.54 | |
| Suicide Death (%) | 0 (0.00) | 8 (21.05) | 0.043 | 5 (15.63) | 0.12 | |
| Alcohol or drug death (%) | 0 (0.00) | 25 (65.79) | 1.072 × 10−6 | 19 (59.36) | 1.31 × 10−5 | |
| vmPFC | N | 20 | 35 | 32 | ||
| Sex = M (%) | 13 (65.00) | 16 (45.70) | 0.27 | 21 (65.60) | >0.99 | |
| AgeDeath mean (SD) | 47.25 (10.38) | 41.11 (11.88) | 0.059 | 41.24 (10.90) | 0.054 | |
| PMI mean (SD) | 30.10 (7.22) | 28.10 (8.50) | 0.38 | 27.31 (7.50) | 0.19 | |
| White non-Hispanic ancestrya n (%) | 14 (70.00) | 28 (80.00) | 0.61 | 27 (84.40) | 0.38 | |
| Smoking (%) | 5 (25.00) | 26 (74.30) | 0.0011 | 22 (68.80) | 0.0053 | |
| Military service (%) | 1 (5.00) | 13 (37.10) | 0.021 | 4 (12.50) | 0.68 | |
| Suicide death (%) | 0 (0.00) | 7 (20.00) | 0.085 | 5 (15.60) | 0.17 | |
| Alcohol or drug death (%) | 0 (0.00) | 24 (68.60) | 3.32E-06 | 19 (59.40) | 0.000056 | |
a
This cohort subjects had primarily white non-Hispanic or African American ancestry. The exception was one control with mixed ancestry. P value for the proportion of ancestry tests the proportion of WNH vs non-WNH ancestry per group.