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. 2021 Sep 13;297(4):101196. doi: 10.1016/j.jbc.2021.101196

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© 2021 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

DRP1 is required for expression of genes that regulate calcium signaling.A, principal component analysis of untargeted transcriptomic profiling of shCTRL (blue) and shDRP1 (pink) cells. B, volcano plot of genes differentially regulated by shDRP1. C, heat map visualization of top 30 differentially regulated genes by shDRP1. D, pathway enrichment analysis of differentially regulated genes. E, schematic illustration of differentially regulated genes involved in calcium signaling and homeostasis. Structures highlighted in shades of red were differentially regulated by shDRP1. Darker shades of red correlate to increased activation.