Table 3.
Changes in potential metabolites in children with metabolic syndrome following the intervention.
| Class | Metabolite | Value of p | pFDR | FC | log2FC |
|---|---|---|---|---|---|
| Amino Acids | Alanine | 9.31E-09 | 1.01E-07 | 0.6596 | −0.6004 |
| Amino Acids | Aspartic acid | 1.64E-07 | 1.24E-06 | 0.4813 | −1.0549 |
| Amino Acids | Creatine | 1.86E-09 | 3.45E-08 | 0.4381 | −1.1908 |
| Amino Acids | Glutamic acid | 1.64E-07 | 1.24E-06 | 0.6658 | −0.5868 |
| Amino Acids | Glycine | 3.73E-09 | 5.85E-08 | 1.4961 | 0.5812 |
| Amino Acids | Homocitrulline | 1.82E-05 | 7.35E-05 | 0.6599 | −0.5997 |
| Amino Acids | Isoleucine | 1.04E-05 | 4.92E-05 | 1.3842 | 0.4691 |
| Amino Acids | Leucine | 4.60E-04 | 1.42E-03 | 0.7844 | −0.3504 |
| Amino Acids | Methylcysteine | 9.31E-09 | 1.01E-07 | 2.3801 | 1.251 |
| Amino Acids | N-Acetylserine | 3.79E-06 | 2.03E-05 | 0.8329 | −0.2637 |
| Amino Acids | Phenylalanine | 1.86E-08 | 1.90E-07 | 0.6225 | −0.6839 |
| Amino Acids | Pipecolic acid | 8.56E-09 | 1.01E-07 | 1.7982 | 0.8465 |
| Amino Acids | Pyroglutamic acid | 1.02E-07 | 9.09E-07 | 0.6617 | −0.5958 |
| Amino Acids | Serine | 9.44E-11 | 3.85E-09 | 1.3458 | 0.4285 |
| Amino Acids | Tryptophan | 1.86E-09 | 3.45E-08 | 0.6943 | −0.5265 |
| Amino Acids | Tyrosine | 3.73E-09 | 5.85E-08 | 0.6829 | −0.5502 |
| Amino Acids | Valine | 5.09E-07 | 3.25E-06 | 0.8015 | −0.3192 |
| Benzenoids | Phenylpyruvic acid | 5.59E-09 | 8.14E-08 | 0.5555 | −0.8481 |
| Bile Acids | DCA | 6.08E-04 | 1.80E-03 | 0.2707 | −1.885 |
| Carbohydrates | Gluconolactone | 9.98E-07 | 5.82E-06 | 0.8304 | −0.2681 |
| Carbohydrates | Glyceric acid | 1.64E-07 | 1.24E-06 | 0.8096 | −0.3047 |
| Carbohydrates | Maltotriose | 4.60E-04 | 1.42E-03 | 0.4748 | −1.0746 |
| Carbohydrates | Xylose | 2.99E-03 | 7.34E-03 | 0.8239 | −0.2795 |
| Carboxylic acids | 2-Methylbutyroylcarnitine | 8.01E-08 | 7.43E-07 | 0.6657 | −0.5869 |
| Carnitines | Acetylcarnitine | 1.01E-05 | 4.90E-05 | 1.5007 | 0.5856 |
| Carnitines | Carnitine | 1.64E-07 | 1.24E-06 | 0.6998 | −0.515 |
| Carnitines | Dodecanoylcarnitine | 1.60E-05 | 6.65E-05 | 0.7302 | −0.4537 |
| Carnitines | Glutarylcarnitine | 8.01E-08 | 7.43E-07 | 0.722 | −0.4698 |
| Carnitines | Isovalerylcarnitine | 4.71E-07 | 3.10E-06 | 0.5972 | −0.7437 |
| Carnitines | Oleylcarnitine | 1.01E-12 | 1.03E-10 | 1.4978 | 0.5828 |
| Carnitines | Palmitoylcarnitine | 7.72E-10 | 2.62E-08 | 1.258 | 0.3311 |
| Carnitines | Propionylcarnitine | 1.86E-09 | 3.45E-08 | 0.4825 | −1.0515 |
| Carnitines | Stearylcarnitine | 8.35E-11 | 3.85E-09 | 1.5441 | 0.6268 |
| Carnitines | 2-Hydroxy-3-methyl butyric acid | 5.14E-06 | 2.56E-05 | 1.5201 | 0.6042 |
| Fatty Acids | Adrenic acid | 1.84E-05 | 7.35E-05 | 1.3389 | 0.421 |
| Fatty Acids | Azelaic acid | 9.98E-07 | 5.82E-06 | 0.6165 | −0.6979 |
| Fatty Acids | Heptadecanoic acid | 3.86E-07 | 2.71E-06 | 0.6052 | −0.7244 |
| Fatty Acids | Heptanoic acid | 2.02E-03 | 5.15E-03 | 0.6635 | −0.5918 |
| Fatty Acids | Oleic acid | 4.16E-05 | 1.57E-04 | 1.2232 | 0.2906 |
| Fatty Acids | AMP | 1.24E-05 | 5.76E-05 | 0.7345 | −0.4452 |
| Nucleotides | 2-Hydroxybutyric acid | 3.79E-06 | 2.03E-05 | 1.9684 | 0.977 |
| Organic Acids | trans-Aconitic acid | 4.81E-17 | 9.82E-15 | 1.8366 | 0.877 |
| Organic Acids | 3-Hydroxybutyric acid | 9.31E-09 | 1.01E-07 | 7.8566 | 2.9739 |
| Organic Acids | alpha-Ketoisovaleric acid | 1.57E-05 | 6.65E-05 | 0.8407 | −0.2503 |
| Organic Acids | cis-Aconitic acid | 1.86E-09 | 3.45E-08 | 1.8296 | 0.8715 |
| Organic Acids | Citric acid | 1.86E-09 | 3.45E-08 | 1.8301 | 0.872 |
| Organic Acids | Guanidoacetic acid | 9.42E-09 | 1.01E-07 | 1.3953 | 0.4806 |
| Organic Acids | Isocitric acid | 3.95E-11 | 2.69E-09 | 1.5129 | 0.5973 |
| Organic Acids | Malic acid | 4.40E-07 | 2.99E-06 | 1.2751 | 0.3506 |
| Organic Acids | Pyruvic acid | 1.60E-05 | 6.65E-05 | 0.696 | −0.5229 |
| Phenols | 4-Hydroxyphenylpyruvic acid | 2.55E-07 | 1.86E-06 | 0.6265 | −0.6747 |
| Primary BAs | GCDCA | 1.13E-03 | 3.07E-03 | 0.5158 | −0.955 |
| SCFAs | 2-Methylpentanoic acid | 5.55E-04 | 1.69E-03 | 0.6013 | −0.7339 |
| SCFAs | 3-Hydroxyisovaleric acid | 2.83E-04 | 9.63E-04 | 0.8201 | −0.2861 |
| SCFAs | Caproic acid | 1.72E-03 | 4.49E-03 | 0.8195 | −0.2871 |
| SCFAs | Propionic acid | 4.42E-06 | 2.31E-05 | 0.7692 | −0.3786 |
| SCFAs | Valeric acid | 5.14E-06 | 2.56E-05 | 0.7388 | −0.4367 |
| Unknown | D-Maltose/Alpha-Lactose | 3.45E-04 | 1.14E-03 | 0.7389 | −0.4365 |
| Unknown | GCA_1 | 2.32E-04 | 8.15E-04 | 0.4336 | −1.2056 |