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. 2021 Oct 8;279(2):825–834. doi: 10.1007/s00405-021-07105-9

Table 2.

Particle concentrations in laryngeal procedures and their comparison with background and coughing data

Cold instruments Microdebrider CO2 laser Reference
Backgrounda Coughing
Total particle concentration, particles/cm3
 Median 0.012 0.024 0.438 0.000 0.036
 Mean ± SD 0.708 ± 8.047 0.030 ± 0.039 0.761 ± 2.437 0.004 ± 0.011 1.601 ± 13.772
 Max 119.898 0.342 36.240 0.144 195.528
Comparisons (p values)
 Background < 0.001 < 0.001 < 0.001
 Coughing 0.753 0.146 < 0.001
< 1 μm particle concentration, particles/cm3
 Median 0.012 0.018 0.426 0.000 0.030
 Mean ± SD 0.705 ± 8.047 0.026 ± 0.039 0.742 ± 2.436 0.004 ± 0.010 1.588 ± 13.751
 Max 119.898 0.342 36.240 0.144 195.510
Comparisons (p values)
 Background < 0.001 < 0.001 < 0.001
 Coughing 0.686 0.152 < 0.001
1–5 μm particle concentration, particles/cm3
 Median 0.000 0.000 0.012 0.000 0.006
 Mean ± SD 0.002 ± 0.004 0.003 ± 0.004 0.017 ± 0.025 0.000 ± 0.002 0.012 ± 0.064
 Max 0.030 0.018 0.276 0.018 1.242
Comparisons (p values)
 Background 0.004 0.013 < 0.001
 Coughing 0.043 0.305 0.064
> 5 μm particle concentration, particles/cm3
 Median 0.000 0.000 0.000 0.000 0.000
 Mean ± SD 0.001 ± 0.002 0.001 ± 0.004 0.001 ± 0.003 0.000 ± 0.001 0.001 ± 0.002
 Max 0.012 0.030 0.024 0.006 0.012
Comparisons (p values)
 Background 0.218 0.005 0.094
 Coughing 0.174 0.089 0.131

Median, mean ± SD, and max calculated from all measured values. Measured minimum value in all laryngeal procedures and reference measurements in all size groups of particles was 0.000

SD standard deviation, Max measured maximum value

p values compared with aerosol concentrations of background were calculated using one-tailed unpaired-samples t test; for comparisons with coughing reference, two-tailed unpaired t test was used. p values < 0.05 were considered significant and presented bolded. Mean differences with 95% confidence intervals are presented in Appendix Table

ͣBackground values presented from all operation rooms where procedures took place. For each procedure type, background was tested separately according to operation room used. Reference data is presented with Italics