Figure 1.

Lactate can preserve cellular survival under glucose starvation. A) Cell proliferation after incubation with different concentrations of lactate for different periods. B) Lactate concentration of the cell culture medium after different incubation periods. C–F) Cell proliferation after incubation with different concentrations of GOx@ZIF‐8 for 24, 48, 72, and 96 h in media containing glucose (10 mm) or glucose (10 mm) + lactate (5 mm). Data are presented as mean ± SD, n = 3, *p < 0.05, **p < 0.01, and ***p < 0.001. Cells without any treatment were set as the control group and cell proliferation of the control group was set as 100%.