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. 2021 Aug 7;8(19):2101467. doi: 10.1002/advs.202101467

Scheme 1.

Scheme 1

The intracellular therapeutic mechanisms of A) GOx mediated cancer starvation therapy and B) dual‐depriving cancer starvation therapy (glucose is depleted by GOx and the cellular influx of exogenous lactate is blocked by MCT1 inhibitor, CHC). Both therapies are conducted by the ZIF‐8 nanoplatforms.