Table 1.

Conditions and reaction yields for the synthesis of 16–25^a

Entry	Pyrrolinone/Isoindolone	Aldehyde	Yield (%)b	Time (h)	Product
1	9	12	80	24	16
2	9	13	41	24	17
3	9	14	79	24	18
4	9	15	61	24	19
5	10	12	96	6	20
6	10	13	70	24	21
7	10	14	66	24	22
8	11	12	49	30	23
9	11	13	49	27	24
10	11	14	94	24	25

^aReactions performed on a 1 mmol scale in 5 mL of EtOH.

^bIsolated Yield.