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. 2021 Oct 7;147(11):981–989. doi: 10.1001/jamaoto.2021.2625

Table 2. Mental Health (MH) and Substance Use Disorder (SUD) Characteristics of Survivors of Head and Neck Cancer (HNC) Before and After Diagnosis With and Without Suicidal Self-directed Violence (SSDV) Events.

MH And SUD diagnoses and treatment encounters No. (%)
Total cohort (n = 7803) Without SSDV (n = 7731) With SSDV (n = 72)
Before HNC diagnosis After HNC diagnosis Before HNC diagnosis After HNC diagnosis Before HNC diagnosis After HNC diagnosis
MH and SUD diagnosesa
PTSD 926 (11.9) 1072 (13.7) 910 (11.8) 1053 (13.6) 16 (22.2) 19 (26.4)
Anxiety disorder 620 (8.0) 1055 (13.5) 608 (7.9) 1028 (13.3) 12 (16.7) 27 (37.5)
Mood disorder 1560 (20.0) 2046 (26.2) 1530 (19.8) 1995 (25.8) 30 (41.7) 51 (70.8)
Any MH diagnosis 1391 (17.8) 1907 (24.4) 1366 (17.7) 1867 (24.1) 25 (34.7) 40 (55.6)
Nicotine SUD 2355 (23.7) 2445 (24.6) 2326 (30.1) 2412 (31.2) 29 (40.3) 33 (45.8)
Alcohol SUD 1245 (12.5) 1356 (13.6) 1229 (15.9) 1330 (17.2) 16 (22.2) 26 (36.1)
Cannabis SUD 203 (2.0) 258 (2.6) 198 (2.6) 244 (3.2) 5 (6.9) 14 (19.4)
Opioid SUD 128 (1.3) 129 (1.3) 123 (1.6) 115 (1.5) 5 (6.9) 14 (19.4)
Any SUD diagnosis 2958 (37.9) 3133 (40.2) 2918 (37.7) 3084 (40.0) 40 (55.6) 49 (68.0)
MH and SUD treatment use
Any MH visits 2198 (28.2) 3401 (43.6) 2157 (27.9) 3340 (43.2) 41 (56.9) 61 (84.7)
MH Treatment encounters,b median (IQR) 4.0 (1-10) 5.0 (1-12) 4.0 (1-10) 23.0 (4-62) 13.0 (3-30) 5.0 (1-11)
Time to first MH treatment encounter, mean (SD), d NA 210.1 (220.4) NA 208.7 (219.6) NA 233.0 (237.4)
Any SUD treatment visits 399 (5.1) 435 (5.6) 388 (5.0) 411 (5.3) 11 (15.3) 24 (33.3)
Time to first SUD treatment encounter, mean (SD), d NA 136.5 (167.2) NA 137.3 (167.4) NA 92.4 (151.4)
SUD Treatment encounters,b median (IQR) 7.0 (2-34) 4.0 (2-23) 7.0 (4-34) 4.0 (2-20) 10.0 (5-94) 16.5 (8-89)
Time to first palliative care encounter, mean (SD), d NA 151.0 (173.7) NA 149.2 (172.0) NA 275.6 (242.4)
Pain variables
Chronic pain 1572 (19.6) 2747 (35.2) 1495 (19.3) 2696 (34.9) 32 (44.4) 51 (70.1)
Prescription opioid MME,c mean (SD) (n = 6880) 50.4 (96.7) 88.8 (133.8) 50.5 (97.3) 77.9 (128.8) 42.6 (35.4) 121.6 (130.6)

Abbreviations: MME, morphine milligram equivalent; NA, not applicable; PTSD, posttraumatic stress disorder.

a

Diagnoses are not mutually exclusive, so total percentage may exceed 100.

b

The MH and SUD treatment encounter medians and IQRs were calculated among those who had at least 1 encounter.

c

Total MME was only calculated for those who were currently prescribed opioids.