TABLE 1.
S. pyogenes isolates and their genotypes
| Isolate no. | Source of isolation/ disease | Combined 16S ribo-typea | Combined mrp typeb | FAFLP profilec |
|---|---|---|---|---|
| R2590 | Hampshire/cellulitis | R-2 | mrp1.6 | A1 |
| R2335 | Wigan/cellulitis | R-2 | mrp1.6 | A1 |
| R2242 | Oxford/septicemia | R-2 | mrp1.6 | A1 |
| R0027 | Nottingham/pneumonia | R-2 | mrp1.6 | A1 |
| R0214 | Norwich/septicemia | R-2 | mrp1.6 | A1 |
| R2588 | Doncaster/pneumonia | R-2 | mrp1.6 | A1 |
| R2657 | London/bacteremia | R-2 | mrp1.6 | A2 |
| R2419 | Salisbury/septicemia | R-2 | mrp1.6 | A2 |
| R1919 | Bishop Auckland/skin infection | R-2 | mrp1.6 | A3 |
| R1567 | Kent/umbilical swab | R-2 | mrp1.6 | A3 |
| R1990 | Basildon/pharyngitis | R-2 | mrp1.6 | A3 |
| R1763 | Blackpool/sore throat | R-2 | mrp1.6 | A3 |
| R0112 | Blackpool/unknown | R-2 | mrp1.6 | A4 |
| R0109 | Nottingham/cellulitis | R-2 | mrp1.6 | A4 |
| R2420 | Salisbury/cellulitis | R-2 | mrp1.6 | A5 |
| R1870 | Manchester/renal disease | R-2 | mrp1.6 | A5 |
| R1848 | Barnsley/vaginitis | R-2 | mrp1.6 | A5 |
| R2193 | Nottingham/sore throat | R-2 | mrp1.6 | A5 |
| R1934 | Exeter/tonsillitis | R-2 | mrp1.6 | A6 |
| R2179 | Nottingham/pneumonia | R-2 | mrp1.6 | A6 |
| R2424 | Macclesfield/necrotizing fasciitis | R-3 | mrp1.6 | A6 |
| R2656 | London/bacteremia | R-2 | mrp1.6 | A6 |
| R2132 | Surrey/septicemia | R-2 | mrp1.6 | A7 |
| R0129 | West Suffolk/pharyngitis | R-2 | mrp1.6 | A7 |
| R2646 | Manchester/septic arthritis | R-2 | mrp1.6 | A7 |
| R0181 | West Suffolk/impetigo | R-2 | mrp1.6 | A8 |
| R2211 | Carmarthen/vaginitis | R-2 | mrp1.6 | A9 |
| R1630 | Leeds/rheumatic fever | R-2 | mrp1.6 | A10 |
| R2468 | Manchester/toxic shock syndrome | R-2 | mrp1.6 | A11 |
| R0019 | London/infected burns | R-2 | mrp1.6 | A12 |
| R2326 | Salisbury/cellulitis | R-2 | mrp1.6 | A13 |
| R2609 | Plymouth/necrotizing fasciitis | R-2 | mrp1.6 | A14 |
| R2509 | Rhyl/bacteremia | R-2 | mrp1.6 | A15 |
| R1968 | Durham/eye infection | R-2 | mrp1.6 | A16 |
| R2437 | Lancaster/pyrexia | R-2 | mrp1.6a | A17 |
| NCTC 8370d | London/scarlet fever | R-2 | mrp1.5 | A18 |
| R583d | Unknown/unknown | R-5 | mrp1.4 | A19 |
| NCTC 2218d | Aberdeen/scarlet fever | R-6 | mrp1.3 | A20 |
| R2518d | Unknown/unknown | R-4 | mrp1.2 | A21 |
| NCTC 8198d | Manchester/scarlet fever | R-1 | mrp1.1 | A22 |
a
Numbers following the combined ribotype (R; obtained with EcoRI and SacI) indicate different patterns of hybridization with the probe.
b
Numbers following the combined mrp indicate a unique RFLP obtained by combining the results of digestion with three endonucleases (SmaI, SfiI, and NgoAIV).
c
FAFLP profiles obtained with the EcoRI+0 and MseI+T primer pair.
d
Isolates with early isolation dates.