Table 1.
Demographic data and medical history of cryptococcosis patients with different immune statuses
| Total N = 255 (%) | IC N = 169 (%) | MID N = 43 (%) | SID N = 43 (%) | P value | |
|---|---|---|---|---|---|
| Demographic data | |||||
| Sex (male) | 160 (62.7) | 113 (66.9) | 24 (54.5) | 23 (54.8) | 0.162 |
| Age (y) | 46.6 ± 13.7 | 46.4 ± 12.8 | 51.8 ± 14.4 | 41.9 ± 14.9 | < 0.001 (#) |
| BMI, kg/m2 | 23.3 ± 3.3 | 23.8 ± 3.0 | 24.3 ± 3.4 | 20.2 ± 2.4 | < 0.001 (*) |
| Contact history | 16 (6.3) | 12 (7.1) | 3 (7.0) | 1 (2.3) | 0.504 |
| Time since diagnosis(d) | 30.0 (14.3, 60.0) | 30.0 (15.0, 60.0) | 30.0 (22.0, 60.0) | 17.5 (9.0, 30.0) | < 0.001 (*) |
| Dissemination | 57 (22.4) | 17 (10.1) | 8 (18.6) | 32 (74.4) | < 0.001 (*) |
| Medical history | |||||
| Diabetes 13 (6.4) 8 (14.6) 0.06 | 25 (9.8) | 0 | 20 (46.5) | 5 (11.6) | |
| Glucocorticoid 38 (69.1) | 42 (16.5) | 0 | 11 (25.6) | 31 (72.1) | |
| Liver dysfunction | 11 (4.3) | 0 | 8 (18.6) | 3 (7.0) | |
| Chemotherapy 05 (9.1) | 6 (2.4) | 0 | 6 (14.0) | 0 | |
| Autoimmune diseases 0 27 (49.1) | 18 (7.1) | 0 | 6 (14.0) | 12 (27.9) | |
| Other renal disease 1 (0.5) 4 (7.3) | 8 (3.1) | 0 | 2 (4.7) | 6 (14.0) | |
| Haemopathy | 6 (2.4) | 0 | 1 (2.3) | 5 (11.2) | |
| AIDS 08 (14.6) | 8 (3.1) | 0 | 0 | 8 (18.6) | |
| Kidney transplant 013 (23.6) | 13 (5.1) | 0 | 0 | 13 (30.2) | |
| Immunosuppressant | 31 (12.2) | 0 | 0 | 31 (72.1) | |
Haemopathy included myelodysplastic syndrome (MDS, n = 2), allergic purpura (n = 1), multiple myeloma (MM, n = 1), lymphoma (n = 1), and haemolytic anaemia (HA, n = 1); Autoimmune diseases included systemic lupus erythematosus (SLE, n = 10), rheumatoid arthritis (RA, n = 3), connective tissue disease (CTD, n = 1), sarcoidosis (n = 1), ankylosing spondylitis (AS, n = 1), Hashimoto thyroiditis (HT, n = 1), and pemphigoid (n = 1); Other renal diseases included nephrotic syndrome (NS, n = 6), IgA nephropathy (IgAN, n = 1), and renal cell carcinoma (RCC, n = 1); Liver dysfunction included hepatic cirrhosis (n = 9) and hepatocellular carcinoma (HCC, n = 2)
BMI, body mass index; *SID vs. IC/MID; #MID vs. IC/SID;