Table 2.
Cytokine production by CD8+ T cells in response to TLR2 activation (pg/ml)
| NC (peripheral) (n = 9) | GC (peripheral) (n = 11) | GC (tumor-infiltrating) (n = 11) | ||||
|---|---|---|---|---|---|---|
| − Pam3Csk4 | + Pam3Csk4 | − Pam3Csk4 | + Pam3Csk4 | − Pam3Csk4 | + Pam3Csk4 | |
| IFN-γ | 782.2 [243.1, 1107] | 778.9 [256.1, 997.0] | 621.7 [334.6, 1008]# | 597.3 [287.1, 1109] | 572.9 [231.8, 983.1]# | 596.1 [229.8, 963.0] |
| TNF-α | 97.14 ± 28.08 | 98.91 ± 10.95 | 76.64 ± 20.35# | 71.90 ± 17.63 | 66.08 ± 18.24# | 70.19 ± 23.73 |
| IL-2 | 108.2 ± 31.39 | 117.0 ± 39.27 | 87.09 ± 21.22# | 90.83 ± 14.93 | 88.18 ± 10.31# | 89.07 ± 19.52 |
| IL-6 | 57.05 ± 13.42 | 55.19 ± 14.27 | 39.21 ± 10.98# | 34.16 ± 9.08 | 40.13 ± 14.24# | 45.29 ± 7.93 |
| IL-8 | 229.4 ± 78.15 | 241.4 ± 67.63 | 164.7 ± 40.42# | 171.3 ± 51.84 | 170.8 ± 48.33# | 166.0 ± 45.72 |
# P < 0.01 compared with NC