Table 4.
Cytokine production in indirect contact coculture system response to TLR2 activation (pg/ml)
| NC (peripheral) (n = 6) | GC (peripheral) (n = 17) | GC (tumor-infiltrating) (n = 17) | ||||
|---|---|---|---|---|---|---|
| − Pam3Csk4 | + Pam3Csk4 | − Pam3Csk4 | + Pam3Csk4 | − Pam3Csk4 | + Pam3Csk4 | |
| IFN-γ | 809.2 ± 113.4 | 880.4 ± 155.3 | 537.4 ± 100.3# | 507.9 ± 90.67 | 521.7 ± 138.4 # | 568.8 ± 99.35 |
| TNF-α | 110.3 ± 34.40 | 102.0 ± 37.79 | 80.09 ± 11.48# | 85.75 ± 10.75 | 78.88 ± 19.55# | 79.89 ± 16.74 |
| IL-2 | 122.4 ± 38.41 | 114.1 ± 19.90 | 93.48 ± 24.61# | 89.49 ± 21.78 | 98.90 ± 29.66# | 97.82 ± 28.72 |
| IL-6 | 87.90 ± 32.24 | 91.03 ± 26.33 | 69.37 ± 9.38# | 71.81 ± 18.29 | 66.75 ± 19.22# | 64.72 ± 18.39 |
| IL-8 | 271.96 ± 86.43 | 272.8 ± 74.72 | 141.75 ± 28.57# | 147.11 ± 23.97 | 146.1 ± 33.22# | 148.0 ± 30.27 |
#P < 0.05 compared with NC