Table 4.

Univariate and multivariate analysis for DFS

	UNIVARIATE		MULTIVARIATE
Variable	HR with 95% CI	p value	HR with 95% CI	p value
Pathological stage
1	1.3 (0.12–14)	0.8500	0.48 (0.02–8.74)	0.616
2	7 (0.95–52)	0.0560	5.79 (0.43–78.08)	0.185
3	14 (1.9–100)	0.0093	30.36 (1.75–526)	0.019
4	30 (3.8–230)	0.0013	–	–
ypT1	2.6 (0.63–11)	0.1800	4.8 (0.72–32.05)	0.104
ypT2	3.6 (1.1–12)	0.0410	1.76 (0.36–8.68)	0.487
ypT3	5.6 (1.7–18)	0.0043	0.95 (0.20–4.37)	0.943
ypT4	4.7 (1.2–18)	0.0250	0.79 (0.15–4.19)	0.784
ypN1	1.9 (0.85–4.4)	0.1100	0.68 (0.23–2.03)	0.487
ypN2	3.3 (1.5–7.3)	3.2e-03	0.55 (0.16–1.89)	0.343
ypN3	4.8 (2.3–10)	4.6e-05	0.39 (0.09–1-54)	0.178
IntraOP MTS	3.9 (2–7.8)	7.6e-05	56.8 (3.5–906)	0.004
Postoperative CT	0.33 (0.2–0.54)	9.3e-06	0.32 (0.19–0.54)	2.3 e-05

Abbreviations: CT chemotherapy; IntraOP MTS intraoperative metastasis; ypN postoperative N stage after preoperative chemotherapy; ypT postoperative T stage after preoperative chemotherapy