Table 4.

Factors Associated With Change in Frailty Status in Multivariable Models. NCI as a Covariate

Baseline Characteristics	Development of Frailty	Resolution of Frailty
	aOR (95% CI)	aOR (95% CI)
NCI	2.06 (.96, 4.48) P = .07
Age (per one year increase)	1.03 (.99, 1.08) P = .13	1.06 (.99, 1.14) P = .12
Alcohol: light drinker vs abstainer		6.30 (1.33, 30.0) P = .02
Alcohol: moderate/heavy drinker vs abstainer		13.3 (1.33, 132) P = .03
Anti-anxiety or depression medications	1.88 (.97, 3.63) P = .06
BMI: obese vs normal	1.76 (.79, 3.92) P = .17
BMI: overweight vs normal	.99 (.42, 2.31) P = .98
BMI: underweight vs normal	8.20 (.69, 97.1) P = .09
Education: ≥12 yrs vs < 12 yrs	.58 (.26, 1.30) P = .19
Race/Ethnicity: Black, non-Hispanic vs White, non-Hispanic	2.30 (1.04, 5.06) P = .04	.32 (.08, 1.35) P = .12
Race/Ethnicity: Hispanic vs White, non-Hispanic	1.42 (0.53, 3.80) P = .49	3.29 (.63, 17.2) P = .16
Female	1.90 (.93, 3.90) P = .08
Cigarette use: current vs never	2.60 (.96, 7.05) P = .06
Cigarette use: former vs never	4.52 (1.85, 11.0) P < .01
CD4 count (per every 50 cells increase)		1.07 (.99, 1.16) P = .11

Characteristics were measured at baseline unless otherwise indicated.

Abbreviations: aOR, adjusted odds ratio; BMI, body mass index; CI, confidence interval.