Table 5.

Factors Associated With Change in Frailty Status in Multivariable Models. NPZ3 as a Covariate

Baseline Characteristics	Development of Frailty	Resolution of Frailty
	aOR (95% CI)	aOR (95% CI)
NPZ3 score (per 1 unit increase in z-score)	.64 (.46, .89) P = .01
Age (per 1 year increase)	1.03 (.99, 1.08) P = .12	1.06 (.99, 1.14) P = .12
Alcohol: light drinker vs abstainer		6.30 (1.33, 29.95) P = .02
Alcohol: moderate/heavy drinker vs abstainer		13.27 (1.33, 132.16) P = .03
Anti-anxiety or depression medications	1.79 (.92, 3.48) P = .09
BMI: obese vs normal	1.77 (.79, 3.96) P = .17
BMI: overweight vs normal	.96 (.41, 2.24) P = .92
BMI: underweight vs normal	8.51 (.70, 102) P = .10
Education: ≥12 yrs vs <12 yrs	.60 (.27, 1.34) P = .21
Race/Ethnicity: Black, non-Hispanic vs White, non-Hispanic	2.33 (1.05, 5.16) P = .04	.32 (.08, 1.35) P = .12
Race/Ethnicity: Hispanic vs White, non-Hispanic	1.22 (.45, 3.30) P = .70	3.29 (.63, 17.19) P = .16
Female	1.69 (.81, 3.53) P = .16
Cigarette use: current vs never	2.43 (.89, 6.59) P = .08
Cigarette use: former vs never	4.34 (1.78, 10.6) P < .01
CD4 count (per every 50 cells increase)		1.07 (.99, 1.16) P = .11

Characteristics were measured at baseline unless otherwise indicated.

Abbreviations: aOR, adjusted odds ratio; BMI, body mass index; CI, confidence interval.