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. 2021 Aug 23:bbab325. doi: 10.1093/bib/bbab325

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© The Author(s) 2021. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com

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Overview of DeepDRIM. A. Representation of the joint gene expression of gene a and gene b as a primary image. B. The neighbor images are generated from the genes with strong positive covariance with gene a or gene b. C. The network architecture of DeepDRIM, including Network A and Network B, which are two stacked convolutional embedding structures designed to process the primary and neighbor images, respectively. Detailed network structures are shown in Supplementary Figure S3. D. An example for the prediction of a cell-type-specific GRN using DeepDRIM.

Inline graphic — Overview of DeepDRIM. A. Representation of the joint gene expression of gene a and gene b as a primary image. B. The neighbor images are generated from the genes with strong positive covariance with gene a or gene b. C. The network architecture of DeepDRIM, including Network A and Network B, which are two stacked convolutional embedding structures designed to process the primary and neighbor images, respectively. Detailed network structures are shown in Supplementary Figure S3. D. An example for the prediction of a cell-type-specific GRN using DeepDRIM.