Table 1.
Characteristic | Patient 1 | Patient 2 | Patient 3 |
---|---|---|---|
Age, y | 80s | 60s | 50s |
Sex | Male | Female | Male |
Preexisting diseases | |||
Cardiovascular risk factorsa | x | x | — |
Cardiovascular diseaseb | x | x | — |
Oncologic disease | x | — | — |
Rheumatic disease | — | x | — |
Smoking history (pack years) | x (40) | — | x (40) |
Lactate dehydrogenase, U/L (reference, ≤240) | 292 | 449 | 414 |
D-dimer, mg/L (reference, ≤0.5) | >30 | 3.65 | 0.92 |
C-reactive protein, mg/dL (reference, ≤0.5) | 42.1 | 25.2 | 5.6 |
IL-6, pg/mL (reference, ≤10) | 2,205 | 646 | 2,093 |
ANA/ENA | |||
ANA titer (reference IIF, <1:100) | 1:100 | 1:1,000 | 1:100 |
ENA (reference IB, negative) | — | — | x (Scl-70) |
ANA, antinuclear antibody; ENA, extractable nuclear antigen; IB, immunoblot; IIF, indirect immunofluorescence; IL-6, interleukin 6; x, present; —, none/absent.
aDiabetes mellitus, dyslipidemia, arterial hypertension, obesity, nicotine abuse.
bCoronary disease, post–myocardial infarction, peripheral arterial vaso-occlusive disease, poststroke, atherosclerosis.