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. 2021 Aug 31:aqab092. doi: 10.1093/ajcp/aqab092

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© American Society for Clinical Pathology, 2021. All rights reserved.For permissions, please e-mail: journals.permissions@oup.com

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Interference studies of Elecsys anti–SARS-CoV-2 spike protein antibody assay. The recovery (%) was assessed vs the hemolysis index (A), icterus index (B), lipemic index (C), and biotin concentration (D). The dotted lines denote a ±10% threshold relative to a recovery of 100%. Both negative (open circles) and positive (closed circles) sample pools were unaffected by up to 1,740 mg/dL of hemoglobin (hemolysis index of approximately 1,600), 60 mg/dL of bilirubin (icteric index of approximately 80), 4,000 mg/dL of triglycerides (lipemic index of approximately 1,800), and 1,000 ng/mL of biotin.