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. 2021 Aug 31:aqab092. doi: 10.1093/ajcp/aqab092

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© American Society for Clinical Pathology, 2021. All rights reserved.For permissions, please e-mail: journals.permissions@oup.com

This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model)

This article is made available via the PMC Open Access Subset for unrestricted re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the COVID-19 pandemic or until permissions are revoked in writing. Upon expiration of these permissions, PMC is granted a perpetual license to make this article available via PMC and Europe PMC, consistent with existing copyright protections.

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Daily spike protein antibody (S-Ab) time course of hospitalized patients with COVID-19. The S-Ab assay was performed on leftover plasma samples collected daily from a total of 11 hospitalized patients infected with COVID-19 during their admission. Each patient is represented by a unique set of symbols. The measured S-Ab concentrations were plotted against the number of days after reported symptom onset (A) and the number of days after initial polymerase chain reaction positivity (B). Of note, S-Ab concentrations were undetectable (<0.4 U/mL) over the course of 9 days for 1 patient (downward facing open triangle).