Table 1.
Characteristics of study participants.
| PB/ELBW | Controls | P-value | |
|---|---|---|---|
| Total, n (% males) | 50 (48%) | 49 (41%) | |
| Cohort 1 (born 1982–1985), n | 21 | 21 | |
| Cohort 2 (born 1991–1992), n | 16 | 13 | |
| Cohort 3 (born 1999–2000), n | 13 | 15 | |
| Gestational age (weeks), median (IQR) | 27 (2) | Term-born | |
| Birthweight (g), mean (SD) | 961 (225) | 3,513 (304) | |
| Small for gestational age, n | 14 (28%) | ||
| Extremely preterm GA <28 weeks, n | 28 (56%) | ||
| Extremely low birthweight <1,000 g, n | 27 (54%) | ||
| Age (years), mean (SD) | 28 (6) | 28 (6) | 0.87 |
| Height (cm), mean (SD) | 168.5 (8.2) | 172.9 (7.7) | 0.01 |
| Weight (kg), mean (SD) | 68.4 (14.8) | 73.1 (13.5) | 0.11 |
| Smokers, n | 4 (8%) | 4 (8%) | 0.98 |
| BMI (kg/m2), mean (SD) | 24.0 (4.2) | 24.4 (4.5) | 0.59 |
| HbA1c (mmol/mol) (SD)a | 32.7 (2.5) | 33.0 (2.6) | 0.62 |
| Systolic BP (mmHg), mean (SD) | 112 (12) | 112 (11) | 0.86 |
| Diastolic BP (mmHg), mean (SD) | 71 (9) | 69 (8) | 0.38 |
| Baseline diameterb (mm), mean (95% CI) | 3.21 (3.07, 3.35) | 3.37 (3.19, 3.54) | 0.17 |
PB/ELBW very preterm born (<29 weeks of gestation) or with extremely low birthweight (<1,000 g). IQR, interquartile range; GA, gestational age; BMI, body mass index; HbA1c, glycosylated hemoglobin; BP, blood pressure.
a
HbA1c was measured in 78% of the PB/ELBW group and 96% of the control group.
b
Baseline diameter of the brachial artery.