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. 2021 Oct 8;50(2):423–436. doi: 10.1007/s15010-021-01699-2

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© The Author(s) 2021, corrected publication 2021

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Fig. 3 — Illustration of antibiotic treatment by clinical phase and antibiotic class. Complicated phase patients are additionally stratified by procalcitonin. Relative percentages are indicated visually by the length of the boxes. Absolute numbers are printed into or next to the respective box. Some antibiotic groups include additional cases not counted in the subgroups due to the documentation process (e.g., “Betalactams”, includes “Penicillin/ Piperacillin”, “Cephalosporins”, “Carbapenems”. “New betalactams” and Betalactams where the exact type is not specified). A patient can both show up in multiple phases (disease progression) and in multiple antibiotic classes (e.g., multiple antibiotic classes used for treatment), but will be counted once only for a given antibiotic class in a phase (e.g., multiple Betalactam treatments of the same subgroup will be counted as one)