Table 3.

The Danish Vaccination Program for Known Central Nervous System Pathogens

Childhood Vaccination Programme:

Diphtheria-tetanus-pertussis-polio-H. influenzae and 13-valent conjugated pneumococcal vaccines are given at 3, 5, and 12 months of age. A booster of diphtheria-tetanus-pertussis-polio is administered at five years of age.

Measles, mumps and rubella are given at 15 months of age with a booster at four years of age.

Conjugated vaccination for H. influenzae was introduced in 1993. For S. pneumoniae, a 7-valent conjugated vaccine was implemented in 2007 and replaced by a 13-valent vaccine in 2010. For pneumococcal vaccinations in adults please see below.

Recommendations of Vaccination of Risk Groups in Denmark (Adults and Children):

Conjugated meningococcal vaccines (Quadrivalent A, C, Y, W-135 and lately also specific conjugated vaccine for serogroup B) are given to house-hold relatives of confirmed invasive meningococcal disease but has not been part of the Danish childhood vaccination program.

Since 2014, the 13-valent conjugated pneumococcal vaccine is strongly recommended to patients with asplenia, cochlear implants, before organ transplantation, dura defects, immunosuppressive conditions (eg HIV or lymphoma), or after documented invasive pneumococcal disease (eg pneumonia, meningitis, bacteremia). A second vaccination with the 23-valent polysaccharide pneumococcal vaccine is advised eight weeks after administration of the conjugate vaccine.

In Denmark, pneumococcal vaccination can also be considered in patients with chronic heart failure, chronic obstructive pulmonary disease, chronic liver- or kidney disease, diabetes mellitus, age> 64 years, asthma, B-cell immuno-deficiency, smokers, occupational hazards (eg welders).