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. Author manuscript; available in PMC: 2021 Oct 8.
Published in final edited form as: J Magn Reson Imaging. 2019 Mar 27;50(5):1468–1477. doi: 10.1002/jmri.26732

TABLE 3.

Differentiation Between Benign and Malignant Lesions Utilizing First Order-Based Statistics (Significant Differences in Bold)

Benign lesions Malignant lesions P-value
IE variance 11.15 (4.17 to 18.55) 5.90 (2.34 to 14.52) 0.137
IE skewness 0.207 (−0.595 to 2.173) 1.132 (−0.112 to 9.592) 0.022
IE kurtosis −0.34 (−1.14 to 8.55) 3.20 (−0.89 to 90.01) 0.032
IE energy 0.090 (0.067 to 0.185) 0.146 (0.078 to 0.979) 0.029
IE entropy 3.66 (2.77 to 3.95) 3.09 (0.08 to 3.80) 0.049
OE variance 9.36 (4.62 to 16.20) 5.64 (2.34 to 11.36) 0.060
OE skewness 0.169 (−0.754 to 2.684) 1.249 (0.365 to 9.592) 0.004
OE kurtosis 0.07 (−1.04 to 10.24) 2.734 (−0.13 to 90.01) 0.010
OE energy 0.097 (0.075 to 0.222) 0.149 (0.087 to 0.979) 0.010
OE entropy 3.56 (2.63 to 3.86) 3.08 (0.08 to 3.70) 0.008
AUEC variance 8.01 (4.64 to 11.63) 4.84 (2.14 to 8.29) 0.094
AUEC skewness 0.188 (−.661 to 1.991) 1.487 (0.053 to 9.592) 0.005
AUEC kurtosis −0.43 (−0.99 to 6.81) 2.866 (−0.68 to 90.01) 0.006
AUEC energy 0.107 (0.087 to 0.181) 0.159 (0.100 to 0.979) 0.008
AUEC entropy 3.45 (2.84 to 3.66) 3.02 (0.08 to 3.46) 0.009

Data are median (range). IE, initial enhancement; OE, overall enhancement; AUEC, area under enhancement curve.