TABLE 6.

Performance Characteristics of the Three Independent Prediction Models

Parameter maps	Training set	Test set
	AUEC (±SE)	AUEC (±SE)	Sensitivity	Specificity	NPV	PPV
IE	0.75 (0.06)	0.78 (0.12)	67%	100%	91%	100%
OE	0.81 (0.05)	0.78 (0.10)	56%	97%	89%	83%
AUEC	0.77 (0.06)	0.76 (0.11)	67%	97%	91%	86%

IE, initial enhancement; OE, overall enhancement; AUEC, area under the enhancement curve; SE, standard error; NPV, negative predictive value; PPV, positive predictive value.

IE map features – age, skewness, energy, f₆ (sum average), low gray run emphasis

OE map features – age, skewness, f₆, high gray run emphasis, long run high gray emphasis

AUEC map features – age, skewness, energy, f₆, f₈ (sum entropy).