Table 2.
Cox regression multivariable HRs and 95% CIs for association between patient characteristics and CVD mortality
| SAIL UK 2000–2015 | Nonmalignant meningioma | Malignant glioma |
|---|---|---|
| Characteristics | HR (95% CI) | HR (95% CI) |
| Gender | ||
| Female | 1 | |
| Male | 1.16 (0.85–1.57) | 2.11 (1.03–4.31)a |
| Age | 1.11 (1.09–1.12) | 1.08 (1.05–1.11)b |
| Area deprivation | ||
| WIMD 5 (least deprived) | 1 | |
| WIMD 4 | 1.10 (0.70–1.71) | 0.74 (0.28–1.94) |
| WIMD 3 | 1.32 (0.84–2.05) | 0.81 (0.30–2.19) |
| WIMD 2 | 1.73 (1.12–2.66)a | 0.63 (0.21–1.9) |
| WIMD 1 (most deprived) | 2.00 (1.30–3.06)c | 1.37 (0.54–3.48) |
| Year of diagnosis | 0.98 (0.86–1.11) | 0.91 (0.83–1.00) |
| Treatment | ||
| Having surgery | 1 | 1 |
| Not having surgery | 6.23 (1.52–25.62) | Nil |
| No information | 1.35 (1.01–1.83) | 1.82 (0.81–4.09) |
| SEER 2005–2015 | Nonmalignant Meningioma | Malignant Glioma |
| Characteristics | HR (95% CI) | HR (95% CI) |
| Gender | ||
| Female | 1.00 | 1.00 |
| Male | 1.64 (1.55–0.74)b | 1.36 (1.18–1.56)b |
| Age | 1.10 (1.10–1.10)b | 1.07 (1.07–1.08)b |
| Ethnicity | ||
| Non-Hispanic White | 1.00 | 1.00 |
| Hispanic (all races) | 0.91 (0.83–1.01) | 1.10 (0.87–1.39) |
| Non-Hispanic Black | 1.48 (1.37–1.60)b | 2.01 (1.61–2.53)b |
| Non-Hispanic Asian or Pacific Islander | 0.83 (0.75–0.94)c | 0.98 (0.71–1.35) |
| Non-Hispanic American Indian/Alaska Native | 0.84 (0.54–1.30) | 1.72 (0.77–3.86) |
| Non-Hispanic Unknow Race | 0.20 (0.08–0.48)b | 0.43(0.06–3.04) |
| Marital status | ||
| Married/Having Partner | 1.00 | 1.00 |
| Single/Separate/Divorced | 1.38 (1.30–1.47)b | 1.43 (1.23–1.65)b |
| Unknown | 1.26 (1.14–1.40)b | 1.22 (0.87–1.71) |
| Year of diagnosis | 0.99 (0.98–1.00)a | 0.96 (0.94–0.99)c |
| Treatment | ||
| Having surgery | 1.00 | 1.00 |
| Not having surgery | 1.34 (1.25–1.43)b | 1.58 (1.36–1.82)b |
| No information | 1.39 (1.05–1.84)a | 0.33 (0.05–2.36) |
HR, hazard ratio; CI, confidence interval; CVD, cardiovascular disease; WIMD, Welsh Index Multiple Deprivation.
a<.05,
b<.001,
c<.01.
Model adjusted for gender, age, WIMD (SIAL UK), ethnicity (SEER US), marital status (SEER US), year of diagnosis, treatment information for surgery.