Table 2.
Characteristics of the included trials
| Question | Trials (n = 50) |
|---|---|
| Journal—no. (%) | |
| Trials | 16 (32%) |
| BMJ Open | 34 (68%) |
| Sponsor—no. (%) | |
| Pharmaceutical/for-profit | 4 (8%) |
| Academic/not-for-profit | 46 (92%) |
| Crossover trial—no. (%) | 0 (0%) |
| Factorial trial—no. (%) | 0 (0%) |
| Non-inferiority/equivalence trial—no. (%) | 1 (2%) |
| Cluster trial—no. (%) | 7 (14%) |
| Intervention type—no. (%) | |
| Pharmacologic | 6 (12%) |
| Surgical | 5 (10%) |
| Psychosocial/behavioural/educational | 18 (36%) |
| Others | 20 (40%) |
| Multiple types | 1 (2%) |
| Planned sample size—median (IQR) | 266 (120, 548) |