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. 2021 Sep 23;28(10):799–810. doi: 10.1038/s41594-021-00656-9

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© The Author(s) 2021

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Fig. 4 — a, The IC-HC forms a compact claw-like conformation in the tail region and grasps the head region (mainly β-ring) of an adjacent OAD unit. The top view of the OAD array clearly shows the TTH interaction. Details are enlarged in the lower right panel. A schematic representation of the tail region of OAD₀ is shown at the lower left. b, A close-up view of the TTH region. The schematic shows how the tail₀ region calipers the β₊₁ ring and restrains its free allosteric response. c, A model for the OAD array formation mechanism. The γ-HC and LCs are not included in the model as they do not contribute to the critical interactions between adjacent OADs.