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Age-adjusted hazard ratio (HR) estimates for risk of primary CVD outcome, major CHD, and total stroke by quartiles of blood pressure variability in ACCORD. Panels A and B show quartiles of CV-SBP and CV-DBP for the primary CVD outcome, respectively. Panels C and D show quartiles of CV-SBP and CV-DBP for major CHD, respectively. Panels E and F show quartiles of CV-SBP and CV-DBP for total stroke, respectively. Results of trend tests for panels A, B, C, and D are all p < 0.001.
