FIGURE 6.

SOX4 overexpression restored LINC00511‐mediated effects on GC cells. A‐B, GC cell migration ability in sh‐LINC00511 and sh‐LINC00511+pcDNA3.1‐SOX4 group was evaluated by EdU and colony formation assays. C‐E, TUNEL, flow cytometry and Western blot analysis of apoptosis‐associated proteins revealed GC cell apoptosis in sh‐LINC00511 and sh‐LINC00511+pcDNA3.1‐SOX4 groups. F‐G, Transwell and Western blot assays were adopted to detect GC cell migration and EMT process in sh‐LINC00511 and sh‐LINC00511+pcDNA3.1‐SOX4 group. H, Sphere formation assay verified sphere formation efficiency in GC cells transfected with sh‐LINC00511 or sh‐LINC00511+pcDNA3.1‐SOX4. **P < .01