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Combination index (CI) of IMIP and TMZ in U251 cells
| IMIP concentration (μM) | TMZ concentration (μM) | Effect of combination | CI value of combination a |
|---|---|---|---|
| 10 | 100 | 0.432 | 0.65561 |
| 10 | 150 | 0.535 | 0.53085 |
| 10 | 200 | 0.745 | 0.39201 |
| 20 | 100 | 0.712 | 0.23324 |
| 20 | 150 | 0.764 | 0.28852 |
| 20 | 200 | 0.848 | 0.29546 |
CI value <1 indicated that there is a synergistic effect of IMIP combined with TMZ.
