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. 2021 Sep 19;25(19):9476–9481. doi: 10.1111/jcmm.16897

TABLE 1.

Concurrent alterations identified in patients

Case 1 (alteration, allele frequency) Case 2 (alteration, allele frequency)
STRN:exon3~ALK:exon20 (25.9%) LMO7:exon15~ALK:exon20 (15.3%)
MET amplification (3.8‐fold) NRG1:c.602A>T (21.0%)
TP53:c.991C>T (6.3%) TP53:c.314G>A (2.2%)
TP53:c.742C>7 (26.8%) TP53:c.140del (1.4%)
BRCA1:c.5347A>C (4.6%) TP53:c.637C>T (0.9%)
BRCA2:c.7835C>A (3.8%)
FANCM:c.3296G>A (6.1%)
IDH1:c.940C>T (4.2%)
LRP1B:c.139T>C (3.3%)
MSH6:c.1589A>G (2.8%)
NTRK2:c.718_719del (5.3%)
PMS1:c.2417C>G (5.1%)
PTPN13:c.2516C>T (17.2%)