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. Author manuscript; available in PMC: 2022 Jan 16.
Published in final edited form as: Mol Psychiatry. 2021 Apr 9;26(11):6937–6951. doi: 10.1038/s41380-021-01094-1

Figure 2. Information used for variant and gene prioritization.

Figure 2.

Detailed description of the “Annotation” fields can be found in the Supplemental Methods and Table 2. PPI: Protein-protein interaction; GO: Gene Ontology; pLI: probability of being loss-of-function intolerant score; mis_z: Z score for the deviation of observed counts from the expected number of missense mutations; TPM: Transcript Per Million.