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. Author manuscript; available in PMC: 2022 Jan 16.
Published in final edited form as: Mol Psychiatry. 2021 Apr 9;26(11):6937–6951. doi: 10.1038/s41380-021-01094-1

Figure 3. Protein-protein interaction (PPI) networks.

Figure 3.

(A) PPI network of the 71 TD top candidate genes. Only genes that can be connected are shown. (B) PPI networks of the 71 TD top candidate genes not in (A). Other NDD_all genes were added as intermediate nodes if they interact with more than one TD top candidate genes. For intermediate nodes, only interactions with top candidate genes were included. (C) PPI network formed by NDD_all genes identified in axoneme (GO:0005930). (D) PPI networks formed by NDD_all genes in synaptic membrane (GO:0097060). To simplify the network, interactions between non-candidate genes were removed. PPI networks were defined by three databases, ConsensusPathDB, STRING, and GIANT_v2. Genes were colored by the gene lists (see Methods for details).