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. 2021 Oct 9;159:78–86. doi: 10.1016/j.ejca.2021.09.027

Table 2.

Symptoms, treatment and outcomes of children with cancer or following haematopoietic stem cell transplantation and SARS-CoV-2 infection confirmed by PCR.

Symptoms, treatment and outcome N (%)
COVID-19 symptoms (n = 89)
  • -

    Fever ≥38°C

 63 (71)
  • -

    Cough

 42 (47)
  • -

    Coryza

 26 (29)
  • -

    Any gastrointestinal symptom

 21 (24)
  • -

    Dyspnoea

 17 (19)
  • -

    Sore throat

 10 (11)
  • -

    Anosmia or loss of taste

 6 (7)
  • -

    Myalgia/arthralgia

 6 (7)
  • -

    Rash

 4 (4)
COVID-19 treatment
Any antiviral therapy (n = 11, 8%)
Oseltamivir 6
Hydroxychloroquine 3
Ribavirin 1
Lopinavir/ritonavir 1
Remdesivir 1
Azithromycin 17
Any adjunctive therapy (n = 13, 10%)
Corticosteroids 11
Immunoglobulin 8
Tocilizumab 5
Convalescent plasma 3
Anticoagulation 1
Supplemental O2 17
Chemotherapy changes (n=100)
Withheld 30 (30)
Modified 6 (6)
Unknown 1 (1)
No change 63 (63)
Outcome
ICU admission 15 (11)
  • -

    Mechanical ventilation

 10
  • -

    Inotropic support

 10
  • -

    ECMO

 0
Disease severity
  • -

    Asymptomatic

 42 (32)
  • -

    Mild

 61 (47)
  • -

    Moderate

 11 (8)
  • -

    Severe

 5 (4)
  • -

    Critical

 12 (9)
Died 5 (4)
  • -

    COVID-19 related

 4 (3)
  • -

    Disease progression

 1 (1)

ICU, intensive care unit; ECMO, extracorporeal membrane oxygenation.