Table 2.
Clinical outcomes and health-related quality-of-life results sub-analysis according to gender
| Parameter | MN + CP (n = 38) | CP alone (n = 41) | MN alone (n = 40) | P-value (MN + CP vs. CP) | P-value (MN + CP vs. MN) | P-value (CP vs. MN) | P-value (ANOVA for three groups comparison) |
|---|---|---|---|---|---|---|---|
| Number of males and females | 10 M/28 F | 8 M/33 F | 10 M/30 F | – | – | – | – |
| Females: | |||||||
| Mean age (SD) | 31.13 (9.56) | 28.33 (5.09) | 31.60 (8.00) | 0.33 | 0.97 | 0.21 | 0.19 |
| G-B before Tx | 2.86 (0.83) | 2.42 (1.02) | 2.87 (1.02) | 0.19 | 1.00 | 0.16 | 0.11 |
| G-B after Tx | 1.89 (1.11) p = 0.0005 | 2.21 (0.95) p = 0.39 | 2.50 (0.92) p = 0.15 | 0.43 | 0.06 | 0.48 | 0.07 |
| DLQI before Tx | 12.89 (6.26) | 6.58 (4.29) | 10.70 (6.44) | 0.0001 | 0.31 | 0.01 | < 0.0001 |
| DLQI after Tx | 7.07 (5.04) p = 0.0003 | 4.67 (3.92) p = 0.06 | 7.27 (5.46) p = 0.03 | 0.13 | 0.99 | 0.09 | 0.06 |
| Males: | |||||||
| Mean age (SD) | 29.00 (6.94) | 29.00 (5.85) | 30.5 (5.83) | 1.00 | 0.85 | 0.87 | 0.83 |
| G-B before Tx | 2.90 (0.83) | 2.86 (0.99) | 2.90 (0.83) | 1.00 | 1.00 | 1.00 | 0.99 |
| G-B after Tx | 2.40 (1.20) p = 0.29 | 2.57 (0.90) p = 0.55 | 2.70 (0.90) p = 0.65 | 0.93 | 0.78 | 0.96 | 0.81 |
| DLQI before Tx | 14.90 (5.11) | 6.71 (3.69) | 9.10 (5.97) | 0.006 | 0.05 | 0.06 | 0.006 |
| DLQI after Tx | 9.20 (5.15) p = 0.023 | 4.43 (3.06) p = 0.20 | 7.40 (5.46) p = 0.56 | 0.11 | 0.68 | 0.40 | 0.13 |
MN – microneedling, CP – chemical peeling, G-B – Goodman and Baron scale, DLQI – Dermatology Life Quality Index, Tx – treatment, M – males, F – females. Numbers in brackets give standard deviation. The p-values given in the “after Tx” cells refer to the pre- and post-treatment comparison. Bold marks statistical significance.