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. 2021 Oct 9;26(10):106501. doi: 10.1117/1.JBO.26.10.106501

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© 2021 The Authors

Published by SPIE under a Creative Commons Attribution 4.0 International License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.

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Fig. 8 — AG825 treatment significantly increased NAD(P)H intensity in both (a) cytoplasmic and (b) nuclear regions in SCC74A and SCC74B cell lines. Calibrated NAD(P)H intensity was normalized to the average intensity of vehicle control cells for each replicate. Significant increase in NAD(P)H intensity following AG825 treatment was observed in both compartments of metabolically inhibited SCC74A and SCC74B cells. Error bars are the SEM for 6 (SCC74A) or 7 (SCC74B) experiments with 5 to 7 images taken per treatment in each experiment (* $p < 0.05$ ; ** $p < 0.01$ ; *** $p < 0.001$ ; **** $p < 0.0001$ ).